Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

This paper discusses results achieved with WIT-OC (OCMI), a precursor media to Renaissance Essential Tumor Medium.

Currently available human tumour cell line panels consist of a small number of lines in each lineage that generally fail to retain the phenotype of the original patient tumour. Here we develop a cell culture medium that enables us to routinely establish cell lines from diverse subtypes of human ovarian cancers with >95% efficiency. Importantly, the 25 new ovarian tumour cell lines described here retain the genomic landscape, histopathology and molecular features of the original tumours.

Download the file