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Wood Breast Cell Model

Cellaria-WoodProductImage

The Wood cell model originates from an infiltrating ductal and lobular carcinoma of the breast, the first in our Cellini series of breast cancer lines.

Product Family: Cellini Breast Cell Models

Disease Area: Cancer

Tissue Type: Breast

Clinical Diagnosis: Infiltrating ductal and lobular carcinoma of the breast

Disease Area: Cancer
Tissue Type: Breast
Clinical Diagnosis: Infiltrating ductal and lobular carcinoma of the breast
Age: 65-69
Sex: Female
Ethnicity: Caucasian
BMI: 33.98
TNM Stage: T2N0M0
Staging Group: IIA
Co-indications: N/A
Medications: Acetaminophen and Hydrocodone, Carvedilol, Omeprazole, Potassium Chloride, Metformin, Levothyroxine, Furosemide, Glipizide, Cyclobenzaprine
Mutations: EGFR:E424Q
Country of Collection: United States
Year of Origin: 2013
Additional Characteristics:

ER-positive

Gene Mutations

Gene Alteration Frequency (%) Exon Result
EGFR E424Q 8 11 Mutated, Variant of Unknown Significance
MYC Amplification

Wood Growth Characteristics

Wood Cell Model Growth Chart
Wood Cell Model Growth Chart

The historical growth curve of Wood demonstrates consistent growth and highlights the lack of cell crisis.

STR Profile

AMEL: X
CSF1PO: 11, 13
D13S317: 9, 14
D16S539: 12, 13
D18S51: 13, 15
D21S11: 29, 31
D3S1358: 14, 18
D5S818: 11, 12
D7S820: 10, 11
D8S1179: 12, 13
FGA: 24, 26
Penta D: 11, 13
Penta E: 13, 14
TH01: 7, 9
TPOX: 9, 11
vWA: 18

Immunohistochemistry

Tumor sample diagnosis was confirmed by histology and immunohistochemical detection of tumor markers.

H&E staining of breast solid tumor specimen
IHC detection of ER

Lineage Markers

Immunofluorescence detection of lineage markers confirm epithelial phenotype using pan-keratin with DAPI overlay.

Tumorsphere Formation

Spontaneous formation of tumorspheres under low-attachment conditions.

Day 1
Day 7

Storage and Stability: Store frozen in liquid nitrogen.

Care and Use Instructions: See protocol for further details

Quality Control: All lots are tested for microbial and viral contamination, cell line cross-contamination, mycoplasma, and consistent growth capabilities. See Certificate of Analysis for further details.

Qty:

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