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Wood Breast Cell Model

Cellaria-WoodProductImage

The Wood cell model originates from an infiltrating ductal and lobular carcinoma of the breast, the first in our Cellini series of breast cancer lines.

Product Family: Cellini Breast Cell Models

Disease Area: Cancer

Tissue Type: Breast

Clinical Diagnosis: Infiltrating ductal and lobular carcinoma of the breast

Disease Area: Cancer
Tissue Type: Breast
Clinical Diagnosis: Infiltrating ductal and lobular carcinoma of the breast
Age: 65-69
Sex: Female
Ethnicity: Caucasian
BMI: 33.98
TNM Stage: T2N0M0
Staging Group: IIA
Co-indications: N/A
Medications: Acetaminophen and Hydrocodone, Carvedilol, Omeprazole, Potassium Chloride, Metformin, Levothyroxine, Furosemide, Glipizide, Cyclobenzaprine
Mutations: EGFR:E424Q
Country of Collection: United States
Year of Origin: 2013
Additional Characteristics:

ER-positive

Gene Mutations

Gene Alteration Frequency (%) Exon Result
EGFR E424Q 8 11 Mutated, Variant of Unknown Significance
MYC Amplification

Wood Growth Characteristics

The historical growth curve of Wood demonstrates consistent growth and highlights the lack of cell crisis.

STR Profile

AMEL: X
CSF1PO: 11, 13
D13S317: 9, 14
D16S539: 12, 13
D18S51: 13, 15
D21S11: 29, 31
D3S1358: 14, 18
D5S818: 11, 12
D7S820: 10, 11
D8S1179: 12, 13
FGA: 24, 26
Penta D: 11, 13
Penta E: 13, 14
TH01: 7, 9
TPOX: 9, 11
vWA: 18

Immunohistochemistry

Tumor sample diagnosis was confirmed by histology and immunohistochemical detection of tumor markers.

H&E staining of breast solid tumor specimen
IHC detection of ER

Lineage Markers

Immunofluorescence detection of lineage markers confirm epithelial phenotype using pan-keratin with DAPI overlay.

Tumorsphere Formation

Spontaneous formation of tumorspheres under low-attachment conditions.

Day 1
Day 7

Storage and Stability: Store frozen in liquid nitrogen.

Care and Use Instructions: See protocol for further details

Quality Control: All lots are tested for microbial and viral contamination, cell line cross-contamination, mycoplasma, and consistent growth capabilities. See Certificate of Analysis for further details.

Qty:

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