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Powder Ovarian Cell Model

Cellaria-PowderProductImage

The Powder cell model originates from serous carcinoma of the ovary, a part of our Raphael series for ovarian cancer lines.

Product Family: Raphael Ovarian Cell Models

Disease Area: Cancer

Tissue Type: Ovary

Clinical Diagnosis: Serous carcinoma of the ovary

Disease Area: Cancer
Tissue Type: Ovary
Clinical Diagnosis: Serous carcinoma of the ovary
Age: 65-69
Sex: Female
Ethnicity: Caucasian
BMI: N/A
TNM Stage: T3cN1M1
Staging Group: IV
Co-indications: N/A
Medications: Adderall, Fosamax, Claritin, Calcium Carbonate and Vitamin D, Effexor, Hydrocodone and Acetaminophen, Triamterene
Mutations: SMO:L23dup
Country of Collection: United States
Year of Origin: 2012
Additional Characteristics:

N/A

Gene Mutations

Gene Alteration Frequency (%) Exon Result
SMO L23dup 28 1 Mutated, Presumed Benign

Powder Growth Characteristics

The historical growth curve of Powder demonstrates consistent growth and highlights the lack of cell crisis.

STR Profile

AMEL: X
CSF1PO: 11, 12
D13S317: 12
D16S539: 9, 11
D18S51: 14, 19
D21S11: 28, 31.2
D3S1358: 14, 16
D5S818: 12
D7S820: 9
D8S1179: 11, 13
FGA: 22, 23
Penta D: 12, 13
Penta E: 13, 17
TH01: 7, 8
TPOX: 8, 9
vWA: 17, 19

Immunohistochemistry

Tumor sample diagnosis was confirmed by histology and immunohistochemical detection of tumor markers.

H&E staining of high-grade serous ovarian solid tumor specimen
IHC detection of PAX 8

Lineage Markers

Immunofluorescence detection of lineage markers confirm epithelial phenotype using CK7 with DAPI overlay.

Tumorsphere Formation

Spontaneous formation of tumorspheres under low-attachment conditions.

Storage and Stability: Store frozen in liquid nitrogen.

Care and Use Instructions: See protocol for further details

Quality Control: All lots are tested for microbial and viral contamination, cell line cross-contamination, mycoplasma, and consistent growth capabilities. See Certificate of Analysis for further details.

Qty:

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